
Potential Oral Health-Brain Volume Connection Revealed

Link Between Oral Health and Alzheimer’s Disease Explored by Japanese Researchers
Researchers from Tohoku University in Japan have recently conducted a study examining the connection between oral health and Alzheimer’s disease. The findings of this study shed light on the potential impact of oral health on the brain, specifically the hippocampus region, which is known to shrink as Alzheimer’s progresses.
The study involved 172 individuals aged 55 and over, all without a history of cognitive disease. These individuals underwent oral examinations, magnetic resonance imaging (MRI), and brain scans twice over a four-year period.
Results from the study revealed a correlation between the decrease in the number of teeth and the severity of gingival diseases, and the rapid shrinkage of the left lobe of the hippocampus. The left lobe of the hippocampus is responsible for controlling thought and memory.
Remarkably, the researchers also found that losing a tooth can be equivalent to aging the brain by 1 to 1.3 years, highlighting the significant impact of oral health on overall brain health.
Satoshi Yamaguchi, one of the authors of the study, emphasized the importance of evaluating the potential link between gum diseases, tooth loss, and dementia. He stated, “Gum diseases and tooth loss, which are caused by inflammation of the tissue around the teeth, are the most common dental diseases. Therefore, it is essential to evaluate its possible link with dementia. Our research revealed the effect of these oral diseases on the part of the brain that controls thinking and memory.”
Yamaguchi also stressed the significance of maintaining good dental health, not just for teeth but also for the brain. He stated, “The findings show that keeping the tooth surrounded by severe gingivitis is associated with brain atrophy (shrinking). It is essential to keep gum disease under control with regular examinations. It may be necessary to extract the tooth and use a prosthesis.”
The study’s results were published in the journal “Neurology,” further supporting the growing body of evidence on the importance of oral health in maintaining cognitive function and preventing neurodegenerative diseases like Alzheimer’s.
With this new insight, it is becoming increasingly clear that preserving oral health is not only crucial for maintaining a healthy smile but also for safeguarding brain health as we age. Regular dental check-ups and proper oral hygiene may play a significant role in reducing the risk of Alzheimer’s disease and other cognitive impairments.





